CREATION OF ANTI-INFLAMMATORY PHARMACEUTICAL COMPOSITIONS (review)

Author:

Syrova Gаnna1ORCID,Petiunina Valentina1ORCID,Makarov Volodymir1ORCID,Lukianova Larysa1ORCID,Сhalenko Natalya1ORCID

Affiliation:

1. Kharkiv National Medical University, Kharkiv, Ukraine

Abstract

The review article summarizes the date of literature and our own research on the creation of more effective and safe domestic combined drugs with a pronounced anti-inflammatory and analgesic effects. Untimely treatment of inflammatory processes often leads to long-term disability and even disability, so today there is an active search for new effective and safe domestic combination drugs with pronounced anti-inflammatory and analgesic effects. The constant search for innovative drugs causes a significant number of diseases, pathological conditions for which treatment with existing drugs is not effective or causes addiction and a large number of side effects. Because of, inflammatory processes can be accompanied by severe pain, spasms, increased convulsive activity of the brain, other disorders of the body, so non-narcotic analgesics and nonsteroidal anti-inflammatory drugs are combined with other drugs that can cause complementary effects or potentiate each other's effects. Caffeine is a useful adjuvant of nonsteroidal anti-inflammatory drugs of various chemical structures in terms of anti-inflammatory and analgesic effects. The review article presents a literature review of the current state of treatment of inflammation and pain, conducting research to expand the therapeutic capabilities of known pharmaceuticals, the creation of pharmaceutical compositions of nonsteroidal anti-inflammatory drugs with caffeine.

Publisher

Kharkiv National Medical University

Subject

General Medicine

Reference72 articles.

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