Mechanism Underlying Post-menopausal Osteoporosis: HIF1α is Required for Osteoclast Activation by Estrogen Deficiency
Author:
Affiliation:
1. Department of Orthopedic Surgery and Department of Integrated Bone Metabolism and Immunology, Keio University School of Medicine, Tokyo, Japan
Publisher
Keio Journal of Medicine
Subject
General Medicine
Link
https://www.jstage.jst.go.jp/article/kjm/64/3/64_2015-0003-RE/_pdf
Reference15 articles.
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3. 3. Ettinger B,Black DM,Mitlak BH,Knickerbocker RK,Nickelsen T,Genant HK,Christiansen C,Delmas PD,Zanchetta JR,Stakkestad J,Glüer CC,Krueger K,Cohen FJ,Eckert S,Ensrud KE,Avioli LV,Lips P,Cummings SR, Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators: Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial. JAMA 1999; 282: 637–645.
4. 4. Matsumoto T,Hagino H,Shiraki M,Fukunaga M,Nakano T,Takaoka K,Morii H,Ohashi Y,Nakamura T: Effect of daily oral minodronate on vertebral fractures in Japanese postmenopausal women with established osteoporosis: a randomized placebo-controlled double-blind study. Osteoporos Int 2009; 20: 1429–1437.
5. 5. Cummings SR,San Martin J,McClung MR,Siris ES,Eastell R,Reid IR,Delmas P,Zoog HB,Austin M,Wang A,Kutilek S,Adami S,Zanchetta J,Libanati C,Siddhanti S,Christiansen C, FREEDOM Trial: Denosumab for prevention of fractures in postmenopausal women with osteoporosis. N Engl J Med 2009; 361: 756–765.
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