Long-term efficacy and safety of low-sodium oxybate in an open-label extension period of a placebo-controlled, double-blind, randomized withdrawal study in adults with idiopathic hypersomnia

Author:

Morse Anne Marie1,Dauvilliers Yves23,Arnulf Isabelle4,Thorpy Michael J.5,Foldvary-Schaefer Nancy6,Chandler Patricia7,Chen Abby7,Hickey Luke8,Black Jed79,Bogan Richard K.10

Affiliation:

1. Janet Weis Children’s Hospital, Geisinger, Danville, Pennsylvania

2. Sleep and Wake Disorders Centre, Department of Neurology, Gui de Chauliac Hospital, Montpellier, France

3. University of Montpellier, INSERM Institute Neuroscience Montpellier (INM), Montpellier, France

4. Sleep Disorder Unit, Pitié-Salpêtrière Hospital and Sorbonne University, Paris, France

5. Albert Einstein College of Medicine, Bronx, New York

6. Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio

7. Jazz Pharmaceuticals, Palo Alto, California

8. Jazz Pharmaceuticals, Philadelphia, Pennsylvania

9. Stanford Center for Sleep Sciences and Medicine, Palo Alto, California

10. University of South Carolina School of Medicine, Columbia, South Carolina

Publisher

American Academy of Sleep Medicine (AASM)

Subject

Neurology (clinical),Neurology,Pulmonary and Respiratory Medicine

Reference36 articles.

1. Idiopathic Hypersomnia

2. Clinical considerations for the diagnosis of idiopathic hypersomnia

3. American Academy of Sleep Medicine . International Classification of Sleep Disorders. 3rd ed . Darien, IL : American Academy of Sleep Medicine ; 2014 .

4. Idiopathic hypersomnia. A series of 42 patients

5. Idiopathic Hypersomnia: A Study of 77 Cases

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