Human derived dimerization tag enhances tumor killing potency of a T-cell engaging bispecific antibody
Author:
Publisher
Informa UK Limited
Subject
Oncology,Immunology,Immunology and Allergy
Link
http://www.tandfonline.com/doi/pdf/10.4161/2162402X.2014.989776
Reference39 articles.
1. Bispecific antibodies engage T cells for antitumor immunotherapy
2. T Cell Costimulus-Independent and Very Efficacious Inhibition of Tumor Growth in Mice Bearing Subcutaneous or Leukemic Human B Cell Lymphoma Xenografts by a CD19-/CD3- Bispecific Single-Chain Antibody Construct
3. Tumor Regression in Cancer Patients by Very Low Doses of a T Cell–Engaging Antibody
4. Targeted Therapy With the T-Cell–Engaging Antibody Blinatumomab of Chemotherapy-Refractory Minimal Residual Disease in B-Lineage Acute Lymphoblastic Leukemia Patients Results in High Response Rate and Prolonged Leukemia-Free Survival
5. Redirected Lysis of Human Melanoma Cells by a MCSP/CD3-bispecific BiTE Antibody That Engages Patient-derived T Cells
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