Ligand association rates to the inner-variable-domain of a dual-variable-domain immunoglobulin are significantly impacted by linker design-Reference-Cited by-同舟云学术

Ligand association rates to the inner-variable-domain of a dual-variable-domain immunoglobulin are significantly impacted by linker design

Published:2011-09 Issue:5 Volume:3 Page:487-494
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

DiGiammarino Enrico L.,Harlan John E.,Walter Karl A.,Ladror Uri S.,Edalji Rohinton P.,Hutchins Charles W.,Lake Marc R.,Greischar Amy J.,Liu Junjian,Ghayur Tariq,Jakob Clarissa G.

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

http://www.tandfonline.com/doi/pdf/10.4161/mabs.3.5.16326

Reference11 articles.

1. Next generation immunotherapeutics—honing the magic bullet

2. Eradication of established tumors in mice by a combination antibody-based therapy

3. Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin

4. Molecular construction and optimization of anti-human IL-1α/β dual variable domain immunoglobulin (DVD-IgTM) molecules

5. Generation and Characterization of a Dual Variable Domain Immunoglobulin (DVD-Ig™) Molecule

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