Flavopiridol induces phosphorylation of AKT in a human glioblastoma cell line, in contrast to siRNA-mediated silencing of Cdk9: Implications for drug design and development-Reference-Cited by-同舟云学术

Flavopiridol induces phosphorylation of AKT in a human glioblastoma cell line, in contrast to siRNA-mediated silencing of Cdk9: Implications for drug design and development

Published:2012-03-15 Issue:6 Volume:11 Page:1202-1216
ISSN:1538-4101
Container-title:Cell Cycle
language:en
Short-container-title:Cell Cycle

Author:

Caracciolo Valentina,Laurenti Giulio,Romano Gaetano,Carnevale Vincenzo,Cimini Anna Maria,Crozier-Fitzgerald Catena,Gentile Warschauer Emilio,Russo Giuseppe,Giordano Antonio

Publisher

Informa UK Limited

Subject

Cell Biology,Developmental Biology,Molecular Biology

Link

http://www.tandfonline.com/doi/pdf/10.4161/cc.11.6.19663

Reference76 articles.

1. PITALRE, a nuclear CDC2-related protein kinase that phosphorylates the retinoblastoma protein in vitro;Graña;Proc Natl Acad Sci U S A,1994

2. Cloning of murine CDK9/PITALRE and its tissue-specific expression in development;Bagella;J Cell Physiol,1998

3. Genomic organization, promoter analysis, and chromosomal mapping of the mouse gene encoding Cdk9;Bagella;J Cell Biochem,2000

4. Regulatory functions of Cdk9 and of cyclin T1 in HIV tat transactivation pathway gene expression;Romano;J Cell Biochem,1999

5. Role of the cyclin-dependent kinase 9-related pathway in mammalian gene expression and human diseases;Romano;Cell Cycle,2008

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