Validation of Polo-like kinase 1 as a therapeutic target in pancreatic cancer cells
Author:
Publisher
Informa UK Limited
Subject
Cancer Research,Pharmacology,Oncology,Molecular Medicine
Link
http://www.tandfonline.com/doi/pdf/10.4161/cbt.21412
Reference52 articles.
1. polo, a mitotic mutant of Drosophila displaying abnormal spindle poles;Sunkel;J Cell Sci,1988
2. polo encodes a protein kinase homolog required for mitosis in Drosophila;Llamazares;Genes Dev,1991
3. Self-regulated Plk1 recruitment to kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation;Kang;Mol Cell,2006
4. Chemical genetics reveals the requirement for Polo-like kinase 1 activity in positioning RhoA and triggering cytokinesis in human cells;Burkard;Proc Natl Acad Sci USA,2007
5. Polo-like kinase 1 triggers the initiation of cytokinesis in human cells by promoting recruitment of the RhoGEF Ect2 to the central spindle;Petronczki;Dev Cell,2007
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