AMBRA1-induced mitophagy: A new mechanism to cope with cancer?
Author:
Affiliation:
1. IRCCS Fondazione Santa Lucia; Rome, Italy
2. Department of Biology; University of Rome Tor Vergata; Rome, Italy
3. Unit of Cell Stress and Survival; Danish Cancer Society Research Center; Copenhagen, Denmark
Publisher
Informa UK Limited
Subject
Cancer Research,Molecular Medicine
Link
https://www.tandfonline.com/doi/pdf/10.4161/23723556.2014.975647
Reference10 articles.
1. Parkin Interacts with Ambra1 to Induce Mitophagy
2. AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1
3. Mitochondrial BCL-2 inhibits AMBRA1-induced autophagy
4. BECN1 is involved in the initiation of mitophagy
5. Modulation of Serines 17 and 24 in the LC3-interacting Region of Bnip3 Determines Pro-survival Mitophagy versus Apoptosis
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