Immunogenic and tolerogenic effects of the chimeric IL-2-diphtheria toxin cytocidal agent Ontak®on CD25+cells
Author:
Publisher
Informa UK Limited
Subject
Oncology,Immunology,Immunology and Allergy
Link
http://www.tandfonline.com/doi/pdf/10.4161/onci.28223
Reference9 articles.
1. Denileukin diftitox (ONTAK) induces a tolerogenic phenotype in dendritic cells and stimulates survival of resting Treg
2. Protein Engineering of DAB-IL-2 Fusion Toxins to Increase Biologic Potency
3. Interleukin 2 receptor-targeted cytotoxicity. Interleukin 2 receptor-mediated action of a diphtheria toxin-related interleukin 2 fusion protein.
4. Interleukin 2-diphtheria toxin fusion protein can abolish cell-mediated immunity in vivo.
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