Evaluation of a reductively activated duocarmycin prodrug against murine and human solid cancers
Author:
Publisher
Informa UK Limited
Subject
Cancer Research,Pharmacology,Oncology,Molecular Medicine
Link
http://www.tandfonline.com/doi/pdf/10.4161/cbt.24348
Reference47 articles.
1. DNA minor groove binders as potential antitumor and antimicrobial agents
2. CC-1065 and the duocarmycins: unraveling the keys to a new class of naturally derived DNA alkylating agents.
3. Molecular basis for sequence selective DNA alkylation by (+)- and ent-(−)-CC-1065 and related agents: Alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity
4. CC-1065 and the Duocarmycins: Understanding their Biological Function through Mechanistic Studies
5. The structure of CC-1065, a potent antitumor agent and its binding to DNA
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