Non–antigen-contacting region of an asymmetric bispecific antibody to factors IXa/X significantly affects factor VIII-mimetic activity-Reference-Cited by-同舟云学术

Non–antigen-contacting region of an asymmetric bispecific antibody to factors IXa/X significantly affects factor VIII-mimetic activity

Published:2015-01-02 Issue:1 Volume:7 Page:120-128
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Sampei Zenjiro¹²,Igawa Tomoyuki¹,Soeda Tetsuhiro¹,Funaki Miho¹,Yoshihashi Kazutaka¹,Kitazawa Takehisa¹,Muto Atsushi¹,Kojima Tetsuo¹,Nakamura Satoshi²,Hattori Kunihiro¹

Affiliation:

1. Research Division; Chugai Pharmaceutical Co., Ltd; Tokyo, Japan

2. Department of Bioengineering; Tokyo Institute of Technology; Yokohama, Japan

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.4161/19420862.2015.989028

Reference33 articles.

1. Engineering the variable region of therapeutic IgG antibodies

2. Antibody therapeutics:

3. Optimization of Fc-mediated effector functions of monoclonal antibodies

4. Switching constant domains enhances agonist activities of antibodies to a thrombopoietin receptor

5. Human constant regions influence the antibody binding characteristics of mouse-human chimeric IgG subclasses

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