Digital Necrosis as Initial Manifestation of Multiple Myeloma: An Unusual Case Report

Author:

Zrikem Hind1,Raissi Abderrahim1,Amrani Idrissi Salma1,Yahyaoui Hicham1,Abbassi Saloua1,Ait Ameur Mustapha1,Chakour Mohammed1

Affiliation:

1. Department of Laboratory Hematology, IBN SINA Military Hospital, Marrakech, Morocco

Abstract

Clinical manifestations of multiple myeloma are variable. The authors report a 68-year-old female who presented to the hospital with bilateral digital necrosis and dry gangrenous toes in both left and right feet. She was diagnosed with IgA-λ multiple myeloma associated with Type I cryoglobulinaemia. Emergency management consisted in hyperhydration (plasmapheresis was not available) and thromboprophylaxis. Necrotic digits were amputated. Chemotherapy (bortezomib, lenalidomide, and dexamethasone) was started with good initial evolution. This uncommon presentation can easily be missed, and clinicians should be aware of a possible underlying malignancy.

Publisher

European Medical Group

Subject

General Medicine

Reference16 articles.

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4. Rajkumar SV et al. International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma. Lancet Oncol. 2014;15(12):e538-e48.

5. Uncommon Presentations of Multiple Myeloma

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