Tubular Handling of Uric Acid and Factors Influencing Its Renal Excretion: A Short Review

Author:

Bruno Cosimo Marcello1,Pricoco Gabriele1,Cantone Damiano1,Marino Elisa1,Bruno Francesca2

Affiliation:

1. Department of Clinical and Experimental Medicine, Section of Internal and Emergency Medicine, University of Catania, Catania, Italy

2. Department of Clinical and Experimental Medicine, Section of Nephrology, University of Catania, Catania, Italy

Abstract

In this review, the authors briefly examine the most recent evidence concerning the role of several proteins involved in tubular urate transport. They also analyse the influence of extracellular volume, electrolyte disorders, acid-base imbalance, and insulin-resistance on renal clearance of uric acid.

Publisher

European Medical Group

Subject

General Medicine

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