Realising the Full Potential of Biosimilars: Interviews with Three Key Opinion Leaders

Author:

Schellekens Huub1,Cornes Paul2,Dreyling Martin3

Affiliation:

1. Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Utrecht, Netherlands

2. Comparative Outcomes Group, Bristol, UK

3. Department of Medicine III, University Hospital, Ludwig Maximilian University (LMU), Munich, Germany

Abstract

It is well documented that biosimilars have great potential to improve access to high-quality cancer care by offering less expensive biological drugs as a result of lower overall development costs than reference products. This has been shown to be the case in numerous examples, such as for the infliximab biosimilar in Norway; however, the overall impact of biosimilar use has been variable.1 In this supplement, three leading experts on biosimilars in cancer care give insights into a number of pertinent issues in the field, wherein there is currently substantial discussion and debate. These valuable insights were obtained from a series of interviews conducted between 19th September and 8th October 2018 by the European Medical Journal with Prof Huub Schellekens, Dr Paul Cornes, and Prof Martin Dreyling. The topics discussed include the extent to which biosimilars can improve access to quality treatment in the context of high cost cancer therapies and the ways in which the potential economic advantages that biosimilars offer can be applied back to health systems. Consideration is also given to the development of biosimilars and the ways in which this process can be simplified and made more cost-effective to result in less expensive products.

Publisher

European Medical Group

Subject

General Medicine

Reference11 articles.

1. National Health Executive. Buzzing about biosimilars. 2018. Available at: http://www.nationalhealthexecutive.com/Comment/buzzing-about-biosimilars. Last accessed: 15 October 2018.

2. Hanahan D, Weinberg RA. The hallmarks of cancer. Cell. 2000;100(1):57-70.

3. IQVIA. Advancing Biosimilar Sustainability in Europe: A Multi-Stakeholder Assessment. 2018. Available at: https://www.iqvia.com/institute/reports/advancing-biosimilar-sustainability-in-europe. Last accessed: 15 October 2018.

4. Dunne SS, Dunne CP. What do people really think of generic medicines? A systematic review and critical appraisal of literature on stakeholder perceptions of generic drugs. BMC Med. 2015;13:173.

5. European Medicines Agency. Biosimilars in the EU: Information guide for healthcare professionals. 2017. Available at: https://www.ema.europa.eu/documents/leaflet/biosimilars-eu-information-guide-healthcare-professionals_en.pdf. Last accessed: 15 October 2018.

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