Treatment Options in Eosinophilic Oesophagitis

Abstract

Eosinophilic oesophagitis (EoE) is an increasingly prevalent chronic inflammatory disorder diagnosed by the presence of oesophageal symptoms and eosinophilic inflammation on endoscopic histology. Treatment of EoE centres around the ‘3 D’s’: drugs, diet, and dilation, which aim to both improve symptoms and prevent potential complications. Potential pharmacologic therapies include acid suppressing agents and corticosteroids, among others. Dietary strategies comprise the elemental diet, the empiric elimination diet, and the allergy testing-directed elimination diet. The therapeutic landscape of EoE is rapidly changing as our understanding of the disease evolves. This review aims to provide a comprehensive discussion of existing EoE therapies and to outline an approach to EoE management.