Abstract
Cancer immunotherapy has moved to the forefront in the treatment of patients with cancer, providing a unique opportunity to achieve dramatic and lasting anti-tumour responses in a variety of tumour types. When it comes to patient selection and development of novel immunotherapeutic agents and combinations, so far we have merely scratched the surface of this therapeutic approach. Leading experts in the field of cancer immunotherapy gathered in Amsterdam, Netherlands, on 21st May 2016 for a Scientific Exchange to discuss the current status of immunotherapy within the field of oncology and explore the future of this evolving therapeutic strategy. Current challenges and limitations regarding the use of immunotherapy were addressed for tumour types such as melanoma, lung cancer, bladder cancer, and renal cell carcinoma (RCC). Recent advances and future directions in the areas of immunotherapy biomarkers and mechanisms of resistance were also examined. Current evidence for combination strategies with immunotherapy was highlighted, including combinations with other immunotherapies or with radiotherapy. Below is a summary of the key points discussed during this scientific exchange.