Microbiome: The Missing Link in Neuropsychiatric Disorders

Abstract

The relationship between intestinal microbiota and the brain has been the focus of attention of the scientific world in recent years; >90% of the articles discussing the microbiome have been published only recently.1 There is a strong and bidirectional relationship between the brain and the gut. Gut bacteria communicate with the intestinal epithelium and the immune system cells, with this communication causing many autoimmune, metabolic, and neuropsychiatric diseases. New horizons have been opened in the understanding and treatment of neuropsychiatry disorders. Microbiota dysbiosis can be restored with faecal microbiota transplantation, dietary arrangements, and probiotics. The efficacy of faecal microbiota transplantation in neuropsychiatric disorders is being investigated currently, and through the manipulation of the composition of intestinal bacteria in a conscious way, the treatment of neuropsychiatric disorders may be performed in a cheaper, easier, and natural way in the near future. Searching through the relevant literature on PubMed, EMBASE, and Google Scholar electronic databases, this is one of the first articles to discuss faecal microbiota transplantation in neuropsychiatric disorders in detail.