CRYOPRECIPITATE PRODUCTION IN RUSSIA: PAST, PRESENT AND FUTURE

Author:

Zhiburt E. B.1ORCID,Chemodanov I. G.2ORCID,Shestakov E. A.1ORCID

Affiliation:

1. National Medical and Surgical Center named after N.I. Pirogov

2. Blood Сentre

Abstract

Aim. To determine the dynamics of cryoprecipitate production in Russian blood service institutions in comparison with such institutions in other countries.Materials and methods. Reports provided by Russian blood service institutions during the 1997–2017 period were analysed, along with European standards for blood collection and transfusion.Results. Over the 1997–2004 period, the number of cryoprecipitate units issued annually ranged from 263,897 (2000) to 297,890 (2002) units. Over the subsequent 8 years, the number of annually released cryoprecipitate decreased to 23,663 units, having reached a historical minimum in 2012. From 2012 to 2017, the number of annually issued cryoprecipitate units increased by 80.0 %, reaching the amount of 42,589 units. Reasons for such a wavelike dynamics in cryoprecipitate production in Russia have been determined. In addition, directions for expanding the use of this product in the correction of hypofibrinogenemia have been identified.Conclusion. Cryoprecipitate should be re-introduced into the practice of clinical transfusiology. To this end, national clinical guidelines for cryoprecipitate application should be developed.

Publisher

National Medical Research Center of Hematology of the Ministry of Health of the Russian Federation

Subject

Hematology

Reference26 articles.

1. Zhiburt E.B. Blood component therapy. Moscow: Pirogov National Medical Surgical Center, 2017. 62 p. (In Russian).

2. Pool J.G. Cryoprecipitated factor VIII concentrate. Thromb Diath Haemorrh Suppl. 1968; 35: 35–40.

3. Stepanova I.P., Belov E.V., Selivanov E.A., Danilova T.N. Production transfusiology of Russia at the present stage. Transfuziologiya. 2000; 1(1): 6–27 (In Russian).

4. Selivanov E.A., Danilova T.N., Degtereva I.N. Russian blood service in 2001. Transfuziologiya. 2002; 3(4): 7–30 (In Russian).

5. Selivanov E.A., Danilova T.N., Bystrov M.V. Russian blood service in 2003. Transfuziologiya. 2004; 5(4): 7–36 (In Russian).

Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Effect of increasing the number of repeated measurements on the accuracy of determining factor VIII activity and fibrinogen concentrations in blood plasma;Russian journal of hematology and transfusiology;2024-03-18

2. First Experience of Production of Pooled Pathogen-Reduced Plasma for Transfusion;Гематология. Трансфузиология. Восточная Европа;2020-05-25

3. Clinical guidelines for cryoprecipitate transfusions;Russian journal of hematology and transfusiology;2020-03-11

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