ALGORITHMS FOR SOLVING PROBLEMS OF PRE-TRANSFUSION IMMUNOHEMATOLOGICAL TESTING

Author:

Pashkova I. A.1ORCID

Affiliation:

1. Research Institute — Regional Clinical Hospital 1 n.a. Prof. S.V. Ochapovsky, Ministry of Healthcare of Krasnodar Krai, Kuban State Medical University, Ministry of Healthcare of the Russian Federation

Abstract

Introduction. Screening and identification of anti-erythrocyte alloimmune antibodies in recipients is an important and necessary step in their testing before blood transfusion.Aim. To formulate algorithms that could facilitate the process of pre-transfusion immunohematological testing.General findings. Such a testing allows the development of post-transfusion reactions and complications to be avoided. The presence of alloantibodies of various specificities and autoantibodies in the test blood may complicate pre-transfusion testing and require the use of additional methods (adsorption, elution, etc.). The author has proposed an effective system of algorithms for conducting immunohematological studies, which can be used to identify patients at risk of developing immune post-transfusion complications and ensure an individual selection of compatible donor blood-transfusion products.

Publisher

National Medical Research Center of Hematology of the Ministry of Health of the Russian Federation

Subject

Hematology

Reference17 articles.

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2. Issitt P.D., Anstree D.J. Applied blood group serology. 4th ed. Montgomery: Scientific Publications; 1998. 1208 p.

3. Milkins C., Berryman J., Cantwell C., et. al. Guidelines for pre-transfusion compatibility procedures in blood transfusion laboratories. British Committee for Standards in Haematology. Transfusion Medicine. 2013; 23(1): 3–35.

4. Mineeva N.V., Bodrova N.N., Zavarzina O.A., et al. Error analysis during immunohematological studies. Vestnik sluzhby krovi. 2007; 2: 3–5 (In Russian).

5. Mineeva N.V. Improving the system for ensuring transfusions compatible with red blood cell antigens. Zdravoohranenie i medicinskaya tekhnika. 2004; 5(9): 25–7 (In Russian).

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