Affiliation:
1. Samara State Medical University
Abstract
Introduction. D-dimer is an important indicator, which reflects the activation of intravascular blood coagulation and fibrinolytic system. There are some data confirming that D-dimer is associated with stroke development in patients with atrial fibrillation. However, D-dimer is not included in modern stoke risk stratification scales in patients with atrial fibrillation.Aim — to analyze the data devoted to the role of D-dimer in stroke risk stratification in patients with atrial fibrillation.General findings. D-dimer, despite several limitations, could be used in clinical practice as an indicator that is associated with stroke development in patients with atrial fibrillation. D-dimer level estimation could help to decide whether to use anticoagulant treatment in patients with low risk of stroke development or in those patients with a single non-sex CHA2DS2-VASc score risk factor.
Publisher
National Medical Research Center of Hematology of the Ministry of Health of the Russian Federation
Reference31 articles.
1. Skvortsova V.I., Shetova I.M., Kakorina E.P., et al. Healthcare system for patients with stroke in Russia. Results of 10-years implementation of the measures aimed at improvement of medical care for patients with acute cerebrovascular events. Annaly klinicheskoy I experimentalnoy nevrologii. 2018; 12(3): 5–12. DOI: 10.25692/ACEN.2018.3.1. (In Russian).
2. Samsonova N.A., Karpova M.I., Moskvicheva M.G. Clinical and expert characteristics of patients with stroke, for the first time recognized as disabled. Zdorov'e i obrazovanie v XXI veke. 2016; 18(10): 35–41. (In Russian).
3. Damulin I.V, Andreev D.A, Salpagarova Z.K. Cardioembolic stroke. Nevrologiya, Neuropsychiatriya, Psychosomatika. 2015; (1): 80–6. DOI: 10.14412/2074-2711-2015-1-80-86. (In Russian).
4. Hindricks G., Potpara T., Dagres N., et al. 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J. 2021; 42(5): 373–498. DOI: 10.1093/eurheartj/ehaa612.
5. Kamel H., Healey J.S. Cardioembolic stroke. Circ Res. 2017; 120(3): 514–26. DOI: 10.1161/CIRCRESAHA.116.308407.
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献