Abstract
Quercetin, a vital natural polyphenolic flavonoid, has diverse pharmacological activities and therapeutic potential. Flavonoids have emerged as a fundamental component in various cosmetic, pharmaceutical, and medicinal formulations. Quercetin is widely recognized for its numerous health benefits, encompassing antioxidant, anti-inflammatory, antiviral, and anticancer properties and due to its wide spectrum of health-promoting effects, quercetin has attracted much attention from dietitians and medicinal chemists. Despite its promising benefits, quercetin faces challenges such as poor solubility, limited water solubility, chemical instability, and low oral bioavailability significantly restrict its potential applications. Strategies such as formulation optimization and nanoparticle-based delivery systems are being explored to enhance its pharmacokinetic profile. Understanding the pharmacology, biochemistry, and pharmacokinetics of quercetin is crucial for optimizing its therapeutic potential and designing precise drug for clinical use. Further scientific research is necessary to elucidate its mechanisms and enhance clinical utilization
Publisher
International Academic Publishing House (IAPH)