Diagnosis and treatment of lymphatic malformations: experience of the surgical department for newborns and infants

Author:

Gurskaya Aleksandra S.1ORCID,Sulavko Mariya A.1ORCID,Bayazitov Rimir R.1ORCID,Ekimovskaya Ekaterina V.1ORCID,Nakovkin Oleg N.1ORCID,Karnuta Inna V.1ORCID,Klepikova Anna A.1ORCID,Sagoyan Garik B.2ORCID,Hagurov Ruslan A.3ORCID,Fisenko Andrey P.1ORCID

Affiliation:

1. National Medical Research Center for Children’s Health

2. N.N. Blokhin National Medical Research Center of Oncology

3. N.F. Filatov Children’s City Hospital

Abstract

Introduction. Lymphatic malformations (LM) are a congenital pathology of lymphatic vessels that arose during embryogenesis. The relevance of the research topic is due to the rarity, variety of clinical manifestations, and the lack of clinical recommendations for treatment. Aim. To evaluate our experience of surgical and conservative treatment of LM in the surgical department for newborns and infants. Materials and methods. We performed a retrospective analysis of infants with various forms of LM treated at our department from 2017 to 2022. The study protocol was approved by the local ethics committee. The patients’ parents gave written voluntary informed consent to participate in the study. Results. Depending on the form of a LM, the infants underwent conservative therapy, sclerotherapy or surgical resection of the LM. Conclusions. Genetic tests for the spectrum of overgrowth syndromes are necessary for all LM patients to clarify the etiology of the process, prevent recurrence and complications.

Publisher

National Medical Research Center for Childrens Health

Subject

General Engineering

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