Atrial fibrillation in real clinical practice at the outpatient stage

Abstract

The aim of the study was to analyze clinical and anamnestic data, the nature of anticoagulant therapy and the incidence of adverse events based on the data of the registry of atrial fibrillation (AF) patients at the outpatient stage (20192020).Methods. The study involved 638 people (56.7% of them women) included in the registry of patients with AF, 68.2±4.5 of age. Inclusion criteria: patients over the age of 18 who applied for a consultation with a cardiologist at a cardiodispensary polyclinic and signed an informed consent.Results. The analysis of clinical and anamnestic data of patients with tachyarrhythmia was carried out. Paroxysmal AF was registered in 311 (48.8%) patients, persistent in 138 (21.6%), long-term persistent in 44 (6.9%) and permanent in 142 (22.7%) patients. The average score on the CHA2DS2-VASc was 4.8±1.8 points, on the HAS-BLED score 2.8±1.6 points, on the 2MACE score 1.3±0.8 points. Compliance to treatment corresponded to 2.5±1.5 points. When analyzing the registry of AF patients, the characteristics of anticoagulant therapy are presented. In fact, 172 (27%) patients took rivaroxaban, 166 (25%) apixaban, 84 (13%) dabigatran and 210 (33%) patients took warfarin. Among those examined, the main cause of death in 30 (4.7%) patients was coronary artery disease, of which two had myocardial infarction.Conclusion. Based on clinical and anamnestic data, a ‘portrait’ of a patient with AF at the outpatient stage is presented, which is characterized by a predominance of the risk of thrombotic complications over the risk of hemorrhagic and coronary events, with low adherence to treatment and implementation of doctor’s recommendations. When analyzing the register of patients with AF, the characteristics of anticoagulant therapy and the causes of adverse outcomes are presented.