AML1/Runx1 as a Versatile Regulator of Hematopoiesis: Regulation of Its Function and a Role in Adult Hematopoiesis

Author:

Kurokawa Mineo

Publisher

Springer Science and Business Media LLC

Subject

Hematology

Reference43 articles.

1. Okuda T, Nishimura M, Nakao M, Fujita Y. RUNX1/AML1: a central player in hematopoiesis. Int J Hematol. 2001;74:252-257.

2. Yamagata T, Maki K, Mitani K. Runx1/AML1 in normal and abnormal hematopoiesis. Int J Hematol. 2005;82:1-8.

3. Miyoshi H, Shimizu K, Kozu T, Maseki N, Kaneko Y, Ohki M. t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1. Proc Natl Acad Sci U S A. 1991;88:10431-10434.

4. Goyama S, Yamaguchi Y, Imai Y, et al. The transcriptionally active form of AML1 is required for hematopoietic rescue of the AML1-deficient embryonic para-aortic splanchnoplcural (P-Sp) region. Blood. 2004;104:3558-3564.

5. Nishimura M,Fukushima-Nakase Y, Fujita Y, et al. VWRPY motif-dependent and -independent roles of AML1/Runx1 transcription factor in murine hematopoietic development. Blood. 2004;103:562-570.

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