Abstract
Many metal complexes with amino acid derived Schiff bases have been synthesized and tested for their biological activity. Thus, the aim of the present study was to evaluate the antimicrobial activity of some binuclear complexes with Schiff bases derived from an aromatic dialdehyde and some amino acids by studying the influence of the tested compounds on the development of microbial biofilms on an inert substrate. The biofilms developed on inert substrate by Klebsiella pneumoniae ESBL+, Citrobacter freundii 1748, Bacillus sp., Serratia marcescens 0804, Staphylococcus aureus ATCC 25923 and Escherichia coli 1576 strains were inhibited at concentrations of the tested compounds between 250 μg∙mL-1 and 500 μg∙mL-1. The results of determining the influence of the tested compounds on the development of microbial biofilms showed that they have an inhibitory effect on microbial adhesion.
Subject
General Medicine,General Earth and Planetary Sciences,General Environmental Science,General Medicine,Ocean Engineering,General Medicine,General Medicine,General Medicine,General Medicine,General Earth and Planetary Sciences,General Environmental Science,General Medicine
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