Dyslipidemia as a Risk Factor in Oral Potentially Malignant Disorder and Oral Cancer Patients

Abstract

BACKGROUND: Dyslipidemia has long been linked to patients with cancer because lipids performance important part in preserving of cell veracity. AIM: To assess and compare the levels of Serum lipid profiles in oral potentially malignant disorders and oral cancer patients. MATERIAL AND METHOD: The present study involves 75 participants who were categorized into three groups. Group 1: Oral cancer consists of 25 subjects with Histopathological confirmed diagnosis of oral cancer. Group 2: Oral precancer consists of 25 subjects with Histopathological inveterate diagnosis of oral potentially malignant. Group 3: Controlled group consists of age and sex matched 25 healthy subjects. RESULTS: Substantial lower levels of mean serum HDL are found in the subjects of OPM and OC group as compared with control group; though, the mean serum CHO, LDL, TG’s, VLDL levels were not significant. CONCUSION: This study concluded that on Lipids assessment HDL was decreased significantly, associated to other lipid profiles. Though, the increasing sign of low HDL-C is an early diagnostic marker for oral potentially malignant and oral Cancer diseases.