Esophageal Melanoma - A Rare Neoplasm

Abstract

A 70 year old man having progressive dysphagia, coronary artery disease (CAD) with an Ejection Fraction (EF) of 30% was detected to have a poorly differentiated esophageal malignancy. Immunohistochemistry (IHC) was positive for HMB 45 and SOX 10 confirming esophageal melanoma. In view of advanced age and poor cardiac function, surgical treatment was not feasible. Palliative esophageal metallic stenting was performed. Immunotherapy was suggested with ICI. We present this case in view of rarity of esophageal melanoma and to stress the need for evaluation with IHC in subjects with poorly differentiated esophageal malignancy.