Synchronous Study of Cefadroxil and Probenecid using Spectrophotometric Method with Expository Agents

Abstract

For the synchronous verification of Cefadroxil and Probenecid in original form and in medicine dual dosages, two much sensitive and accurate spectrophotometric techniques have been derived. Using these techniques, a novel idea of area under the curve- AUC-is put forth for the synchronous calculated of two medicines. DDQ-(2,3-Dichloro-5,6-Dicyano-1,4- Benzoquinone) is used an expository reagent in Method A, and between 389nm to 691nm to DDQ, applied and verified. p-CA-(p-Chloranilicacid: 2,5–Dichloro-3,6– dihydroxy-1,4–benzoquinone) an expository reagent and the between 399nm and 701nm to p-CA are used and verified in Method B. Techniques created, used in calibration plots by two expository reagents respectively i.e., DDQ and p-CA. Optical, expository limits to the single and synchronous verification of Cefadroxil and Probenecid are shown in tables. The procedures are valued and contrast to HPLC, with standard deviation- SD, t-test and F-test.