Creating and Evaluating Herbal Anti-Ageing Cream Contains Pomegranate Seed Oil

Abstract

 Introduction: The skin is the most important exposed a part of the body, is crucial in establishing social bonds and defending against environmental harm. In the present scenario to look attractive is a primary concern for the growing population in order to maintain social integrity and well being. However cell death is a natural process but due to highly stressful environmental conditions now a day’s skin aging is a primary concern for dermatologists. In the present research work we aim to develop a novel anti-ageing cream for the prevention and treatment of unnatural skin ageing by utilizing pomegranate seed oil.  Method: The pomegranate seed oil was purchased from Amarnath export Bangalore Karnataka. The preparation of anti-aging cream was accomplished through conventional method by taking pomegranate seed oil as an oily phase and stearic acid as an emulsifying agent. The formulation was optimized by varying the concentration of aqueous and oily phase.  Result and Discussion: The pH of the developed cream was found to be 7.2 ± 1.2 and viscosity was found to be 5639±2.51cps. Furthermore the spreadibility of the developed cream was found to be 26.6 ±0.2 gm*cm/sec. The developed formulation showed no skin irritation or erythema and also it was easily washable from skin. The stability study of the formulation was studied for 3 month at room temperature (25oC) which suggests high stability as no indication of cracking, phase separation or any other visual change was observed. Furthermore the developed formulation was analyzed through in vivo animal model(Albino wistar rat) which suggest high biocompatibility and potential in the management of skin ageing.  Conclusion: In conclusion we have developed a novel pomegranate seed oil based anti-aging cream for the prevention and treatment of unnatural skin ageing caused by the vulnerable environmental conditions. The developed formulation was analyzed through extensive in vitro and in vivo characterization which proves the potential of the developed cream in the management of unnatural skin ageing.