The Expanding Genetic Toolbox of the Wasp Nasonia vitripennis and Its Relatives

Abstract

Abstract The parasitoid wasp Nasonia represents a genus of four species that is emerging as a powerful genetic model system that has made and will continue to make important contributions to our understanding of evolutionary biology, development, ecology, and behavior. Particularly powerful are the haplodiploid genetics of the system, which allow some of the advantages of microbial genetics to be applied to a complex multicellular eukaryote. In addition, fertile, viable hybrids can be made among the four species in the genus. This makes Nasonia exceptionally well suited for evolutionary genetics approaches, especially when combined with its haploid genetics and tractability in the laboratory. These features are complemented by an expanding array of genomic, transcriptomic, and functional resources, the application of which has already made Nasonia an important model system in such emerging fields as evolutionary developmental biology and microbiomics. This article describes the genetic and genomic advantages of Nasonia wasps and the resources available for their genetic analysis.