A Balance Between Euchromatic (JIL-1) and Heterochromatic [SU(VAR)2-5 and SU(VAR)3-9] Factors Regulates Position-Effect Variegation in Drosophila-Reference-Cited by-同舟云学术

A Balance Between Euchromatic (JIL-1) and Heterochromatic [SU(VAR)2-5 and SU(VAR)3-9] Factors Regulates Position-Effect Variegation in Drosophila

Published:2011-07-01 Issue:3 Volume:188 Page:745-748
ISSN:1943-2631
Container-title:Genetics
language:en
Short-container-title:

Author:

Wang Chao¹,Girton Jack¹,Johansen Jørgen¹,Johansen Kristen M¹

Affiliation:

1. Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, Iowa 50011

Abstract

Abstract In this study, we show that the haplo-enhancer effect of JIL-1 has the ability to counterbalance the haplo-suppressor effect of both Su(var)3-9 and Su(var)2-5 on position-effect variegation, providing evidence that a finely tuned balance between the levels of JIL-1 and the major heterochromatin components contributes to the regulation of gene expression.

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

https://academic.oup.com/genetics/article-pdf/188/3/745/42143920/genetics0745.pdf

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