The mRNA Decay Pathway Regulates the Expression of the Flo11 Adhesin and Biofilm Formation in Saccharomyces cerevisiae-Reference-Cited by-同舟云学术

The mRNA Decay Pathway Regulates the Expression of the Flo11 Adhesin and Biofilm Formation in Saccharomyces cerevisiae

Published:2012-08-01 Issue:4 Volume:191 Page:1387-1391
ISSN:1943-2631
Container-title:Genetics
language:en
Short-container-title:

Author:

Lo Tricia L¹,Qu Yue¹,Uwamahoro Nathalie¹,Quenault Tara¹,Beilharz Traude H¹,Traven Ana¹

Affiliation:

1. Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia

Abstract

Abstract Regulation of the FLO11 adhesin is a model for gene expression control by extracellular signals and developmental switches. We establish that the major mRNA decay pathway regulates FLO11 expression. mRNA deadenylation of transcriptional repressors of FLO11 by the exonuclease Ccr4 keeps their levels low, thereby allowing FLO11 transcription.

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

https://academic.oup.com/genetics/article-pdf/191/4/1387/42121199/genetics1387.pdf

Reference34 articles.

1. Widespread use of poly(A) tail length control to accentuate expression of the yeast transcriptome;Beilharz;RNA,2007

2. Amino acid starvation and Gcn4p regulate adhesive growth and FLO11 gene expression in Saccharomyces cerevisiae;Braus;Mol. Biol. Cell,2003

3. Choosing the right lifestyle: adhesion and development in Saccharomyces cerevisiae;Bruckner;FEMS Microbiol. Rev.,2012

4. Feedback control of morphogenesis in fungi by aromatic alcohols;Chen;Genes Dev.,2006

5. Cell wall integrity is linked to mitochondria and phospholipid homeostasis in Candida albicans through the activity of the post-transcriptional regulator Ccr4-Pop2;Dagley;Mol. Microbiol.,2011

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Current insight into the role of mRNA decay pathways in fungal pathogenesis;Microbiological Research;2024-06

2. Post-transcriptional and translational control of the morphology and virulence in human fungal pathogens;Molecular Aspects of Medicine;2021-10

3. Epitope-tagged yeast strains reveal promoter driven changes to 3′-end formation and convergent antisense-transcription from common 3′ UTRs;Nucleic Acids Research;2015-10-19

4. Two-Dimensionality of Yeast Colony Expansion Accompanied by Pattern Formation;PLoS Computational Biology;2014-12-11

5. Coupling mRNA Synthesis and Decay;Molecular and Cellular Biology;2014-11-15