1. Department of Human Genetics, Faculty of Medicine, McGill University, Montreal, Quebec H3A 1B1, Canada
2. Department of Obstetrics and Gynecology, Faculty of Medicine, McGill University, and the Research Institute of the McGill University Health Centre, Montreal, Quebec H3A 1A1, Canada
3. McGill University and Genome Quebec Innovation Centre, Montreal, Quebec H3A 1A4, Canada and
4. Hospital for Sick Children, Research Institute, Program in Genetics and Genome Biology, Toronto, Ontario M5G 1L7 and the Department of Public Health Sciences, University of Toronto, Toronto, Ontario M5T 3M7, Canada