Genetic Basis of Aerobically Supported Voluntary Exercise: Results from a Selection Experiment with House Mice

Author:

Hillis David A1,Yadgary Liran2,Weinstock George M3,Pardo-Manuel de Villena Fernando2,Pomp Daniel2,Fowler Alexandra S4,Xu Shizhong5,Chan Frank6,Garland Theodore4

Affiliation:

1. Genetics, Genomics, and Bioinformatics Graduate Program, University of California, Riverside, California 92521

2. Department of Genetics, University of North Carolina at Chapel Hill, North Carolina 27599

3. The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut 06032

4. Department of Evolution, Ecology, and Organismal Biology, University of California, Riverside, California 92521

5. Department of Botany and Plant Sciences, University of California, Riverside, California 92521

6. Friedrich Miescher Laboratory of the Max Planck Society, 72076 Tübingen, Germany

Abstract

Abstract House mice from 4 replicate lines selectively bred for 61 generations for voluntary wheel-running behavior were compared with 4 non-selected control lines using multiple genome-wide analytical techniques on both haplotype and single nucleotide polymorphism data......

Publisher

Oxford University Press (OUP)

Subject

Genetics

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