Naive Application of Permutation Testing Leads to Inflated Type I Error Rates-Reference-Cited by-同舟云学术

Naive Application of Permutation Testing Leads to Inflated Type I Error Rates

Published:2008-01-01 Issue:1 Volume:178 Page:609-610
ISSN:1943-2631
Container-title:Genetics
language:en
Short-container-title:

Author:

Churchill G A¹,Doerge R W²

Affiliation:

1. The Jackson Laboratory, Bar Harbor, Maine 04609 and

2. Department of Statistics, Purdue University, West Lafayette, Indiana 47907

Abstract

Abstract Failure to account for family structure within populations or in complex mating designs via uninformed applications of permutation testing will lead to inflated type I error rates. Careful consideration of the design factors is essential since some situations allow several valid permutation strategies, and the choice that maximizes statistical power will not always be intuitive.

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

https://academic.oup.com/genetics/article-pdf/178/1/609/42095474/genetics0609.pdf

Reference5 articles.

1. Permutation tests for multi-factorial analysis of variance

2. Empirical threshold values for quantitative trait mapping.

3. Assessing the Significance of Quantitative Trait Loci in Replicable Mapping Populations

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