Direct Evidence for Postmeiotic Transcription During Drosophila melanogaster Spermatogenesis

Author:

Vibranovski Maria D1,Chalopin Domitille S2,Lopes Hedibert F3,Long Manyuan1,Karr Timothy L4

Affiliation:

1. Department of Ecology and Evolution, University of Chicago, Chicago, Illinois, 60637

2. Ecole Normale Supérieure de Lyon, Lyon 69007, France

3. Booth School of Business, University of Chicago, Chicago, Illinois, 60637 and

4. Biodesign Institute, Arizona State University, Tempe, Arizona, 85287

Abstract

Abstract Extensive gene expression during meiosis is a hallmark of spermatogenesis. Although it was generally accepted that RNA transcription ceases during meiosis, recent observations suggest that some transcription occurs in postmeiosis. To further resolve this issue, we provide direct evidence for the de novo transcription of RNA during the postmeiotic phases. These results strengthen the newly emerging notion that postmeiotic transcription is dynamic and integral to the overall process of spermatogenesis.

Publisher

Oxford University Press (OUP)

Subject

Genetics

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