Drosophila ATM and Mre11 Are Essential for the G2/M Checkpoint Induced by Low-Dose Irradiation-Reference-Cited by-同舟云学术

Drosophila ATM and Mre11 Are Essential for the G2/M Checkpoint Induced by Low-Dose Irradiation

Published:2005-10-01 Issue:2 Volume:171 Page:845-847
ISSN:1943-2631
Container-title:Genetics
language:en
Short-container-title:

Author:

Bi Xiaolin,Gong Min,Srikanta Deepa¹,Rong Yikang S¹

Affiliation:

1. Laboratory of Molecular Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892

Abstract

Abstract Others have suggested recently that the conserved ATM checkpoint kinase is minimally involved in controlling the G2/M checkpoint in Drosophila that serves to prevent mitotic entry in the presence of DNA damage. Our data indicate that both ATM and its regulator Mre11 are important for the checkpoint and that their roles become essential when animals are challenged with a low dose of X rays or when they have compromised checkpoint function of the ATM-related ATR kinase.

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

https://academic.oup.com/genetics/article-pdf/171/2/845/42066146/genetics0845.pdf

Reference18 articles.

1. Cell cycle checkpoint signaling through the ATM and ATR kinases

2. Telomere Protection without a Telomerase

3. mus304 encodes a novel DNA damage checkpoint protein required during Drosophila development

4. Chk2 Activation Dependence on Nbs1 after DNA Damage

Cited by 31 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Wnt signaling modulates the response to DNA damage in the Drosophila wing imaginal disc by regulating the EGFR pathway;PLOS Biology;2024-07-24

2. Wnt signaling modulates the response to DNA damage in theDrosophilawing imaginal disc by regulating the EGFR pathway;2024-02-13

3. Profiling ATM regulated genes in Drosophila at physiological condition and after ionizing radiation;Hereditas;2022-10-21

4. Regulation and coordination of the different DNA damage responses in Drosophila;Frontiers in Cell and Developmental Biology;2022-09-06

5. Genomic instability and cancer: lessons from Drosophila;Open Biology;2020-06