A Role for Caenorhabditis elegans Chromatin-Associated Protein HIM-17 in the Proliferation vs. Meiotic Entry Decision-Reference-Cited by-同舟云学术

A Role for Caenorhabditis elegans Chromatin-Associated Protein HIM-17 in the Proliferation vs. Meiotic Entry Decision

Published:2007-04-01 Issue:4 Volume:175 Page:2029-2037
ISSN:1943-2631
Container-title:Genetics
language:en
Short-container-title:

Author:

Bessler Jessica B¹,Reddy Kirthi C¹,Hayashi Michiko¹,Hodgkin Jonathan²,Villeneuve Anne M¹

Affiliation:

1. Department of Developmental Biology and Department of Genetics, Stanford University School of Medicine, Stanford, California 94305 and

2. Genetics Unit, Department of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom

Abstract

Abstract Chromatin-associated protein HIM-17 was previously shown to function in the chromosomal events of meiotic prophase. Here we report an additional role for HIM-17 in regulating the balance between germ cell proliferation and meiotic development. A cryptic function for HIM-17 in promoting meiotic entry and/or inhibiting proliferation was revealed by defects in germline organization in him-17 mutants grown at high temperature (25°) and by a synthetic tumorous germline phenotype in glp-1(ar202); him-17 mutants at 15°.

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

https://academic.oup.com/genetics/article-pdf/175/4/2029/42187351/genetics2029.pdf

Reference37 articles.

1. Genetic and cytological characterization of the recombination protein RAD-51 in Caenorhabditis elegans

2. glp-1 Is required in the germ line for regulation of the decision between mitosis and meiosis in C. elegans

3. A Conserved Checkpoint Monitors Meiotic Chromosome Synapsis in Caenorhabditis elegans

4. gon-14 Functions With Class B and Class C Synthetic Multivulva Genes to Control Larval Growth in Caenorhabditis elegans

5. C. elegans mre-11 is required for meiotic recombination and DNA repair but is dispensable for the meiotic G2 DNA damage checkpoint

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