Amino Acid Substitutions in the Caenorhabditis elegans RNA Polymerase II Large Subunit AMA-1/RPB-1 that Result in α-Amanitin Resistance and/or Reduced Function
Author:
Affiliation:
1. Department of Biology and
2. Biochemistry, Cell and Developmental Biology Program, Emory University, Atlanta, Georgia 30322
3. Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia V6T1Z4, Canada
Abstract
Publisher
Oxford University Press (OUP)
Subject
Genetics (clinical),Genetics,Molecular Biology
Link
http://academic.oup.com/g3journal/article-pdf/1/6/411/37071289/g3journal0411.pdf
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3. The sua8 suppressors of Saccharomyces cerevisiae encode replacements of conserved residues within the largest subunit of RNA polymerase II and affect transcription start site selection similarly to sua7 (TFIIB) mutations.;Berroteran;Mol. Cell. Biol.,1994
4. Structural basis of transcription inhibition by alpha-amanitin and implications for RNA polymerase II translocation.;Brueckner;Nat. Struct. Mol. Biol.,2008
5. Fine-structure genetics of ama-1, an essential gene encoding the amanitin-binding subunit of RNA polymerase II in Caenorhabditis elegans.;Bullerjahn;Genetics,1988
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