Abstract
BACKGROUND The use of antibiotics as prophylactic prescriptions remains a controversy in dentistry. The current study was done to evaluate the necessity of antibiotic administration following dental extraction among population of 30 – 60 year old age groups. METHODS This is a triple blinded trial with trial registry number CTRI / 2019 / 12 / 022342 in which the 60 study participants were randomized and allocated in a ratio of 1 : 1 : 1 to three groups A (amoxicillin 500 mg t.d.s), B (clindamycin 150 mg t.d.s as a mouthrinse), C (no antibiotic) by lot method. The study proceeded after ethical committee approval and informed consent from the participants. Medically compromised patients, patients in menstruation period, lactation and pregnancy period, test drug hypersensitive patients, tooth with abscess or cyst were excluded and patients of 30 – 60 years old reporting with the complaint to Best Dental Science College, Madurai, were included in the study. The tooth was extracted, and evaluated on 3rd, 7th and 14th day post-operatively. RESULTS The non healing parameters were observed in percentages of 9.7, 6.2 and 6.2 in group A, B and C group during the 14th day clinical evaluation. The presence of non-healing parameters was insignificant between three groups. CONCLUSIONS Prophylactic antibiotics following dental extraction is unnecessary until the patient is at a state of high risk of infection. Thereby, as a dentist we could combat a step towards a developing major public health problem, “Antibiotic Resistance”. KEY WORDS Drug Resistance, Tooth Extraction, Drug Utilization, Antibiotic Awareness, Prophylaxis
Publisher
Akshantala Enterprises Private Limited