Organ Preservation in Rectal Cancer After Chemoradiation: Should We Extend the Observation Period in Patients with a Clinical Near-Complete Response?

Author:

Hupkens Britt J. P.,Maas Monique,Martens Milou H.,van der Sande Marit E.,Lambregts Doenja M. J.,Breukink Stéphanie O.,Melenhorst Jarno,Houwers Janneke B.,Hoff Christiaan,Sosef Meindert N.,Leijtens Jeroen W. A.,Berbee Maaike,Beets-Tan Regina G. H.,Beets Geerard L.

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Surgery

Reference28 articles.

1. Maas M, Nelemans PJ, Valentini V, et al. Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: a pooled analysis of individual patient data. Lancet Oncol 2010; 11(9):835–44.

2. Habr-Gama A, Perez RO, Nadalin W, et al. Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results. Ann Surg 2004; 240(4):711–7; discussion 717-8.

3. Maas M, Beets-Tan RG, Lambregts DM, et al. Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer. J Clin Oncol 2011; 29(35):4633–40.

4. Smith JD, Ruby JA, Goodman KA, et al. Nonoperative management of rectal cancer with complete clinical response after neoadjuvant therapy. Ann Surg 2012; 256(6):965–72.

5. Ayloor SR KS, Jayanand SB, et al. Complete clinical response to neoadjuvant chemoradiation in rectal cancers: can surgery be avoided? Hepatogastroenterology 2013;60(123):410–414.

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