ASO Author Reflections: Neoadjuvant Immunotherapy for Merkel Cell Carcinoma with Clinically Detected Regional Lymph Node Metastasis?

Author:

Chang Jenny H.ORCID,Woo Kimberly P.,Naffouje Samer A.

Publisher

Springer Science and Business Media LLC

Reference5 articles.

1. Reijers ILM, Menzies AM, van Akkooi ACJ, Versluis JM, van den Heuvel NMJ, Saw RPM, Pennington TE, Kapiteijn E, van der Veldt AAM, Suijkerbuijk KPM, Hospers GAP, Rozeman EA, Klop WMC, van Houdt WJ, Sikorska K, van der Hage JA, Grünhagen DJ, Wouters MW, Witkamp AJ, Zuur CL, Lijnsvelt JM, Torres Acosta A, Grijpink-Ongering LG, Gonzalez M, Jóźwiak K, Bierman C, Shannon KF, Ch’ng S, Colebatch AJ, Spillane AJ, Haanen JBAG, Rawson RV, van de Wiel BA, van de Poll-Franse LV, Scolyer RA, Boekhout AH, Long GV, Blank CU. Personalized response-directed surgery and adjuvant therapy after neoadjuvant ipilimumab and nivolumab in high-risk stage III melanoma: the PRADO trial. Nat Med. 2022;28(6):1178–88. https://doi.org/10.1038/s41591-022-01851-x.

2. Topalian SL, Bhatia S, Amin A, Kudchadkar RR, Sharfman WH, Lebbé C, Delord JP, Dunn LA, Shinohara MM, Kulikauskas R, Chung CH, Martens UM, Ferris RL, Stein JE, Engle EL, Devriese LA, Lao CD, Gu J, Li B, Chen T, Barrows A, Horvath A, Taube JM, Nghiem P. Neoadjuvant nivolumab for patients with resectable Merkel cell carcinoma in the CheckMate 358 trial. J Clin Oncol. 2020;38(22):2476–87. https://doi.org/10.1200/JCO.20.00201.

3. Bilusic M. What are the advantages of neoadjuvant immunotherapy over adjuvant immunotherapy? Expert Rev Anticancer Ther. 2022;22(6):561–3. https://doi.org/10.1080/14737140.2022.2069097.

4. Chang JH, Remulla D, Wehrle C, et al. The role of neoadjuvant immunotherapy in the management of Merkel cell carcinoma with clinically detected regional lymph node metastasis. Ann Surg Oncol. 2024. https://doi.org/10.1245/s10434-024-15478-4.

5. Treatment Clinical Trials for Merkel Cell Cancer—NCI. Published June 13, 2017. https://www.cancer.gov/research/participate/clinical-trials/disease/merkel-cell/treatment. Accessed 13 May 2024.

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