Flavonoids kaempferol (KAE) and quercetine (QUE) inhibited proliferation of human leukemia THP-1 cells by up regulation of pro-apoptotic protein Bax and caspase 3/8 expression and down regulation of anti-apoptotic proteins Bcl-2, Bcl-xl and Mcl-1 expression-Reference-Cited by-同舟云学术

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Flavonoids kaempferol (KAE) and quercetine (QUE) inhibited proliferation of human leukemia THP-1 cells by up regulation of pro-apoptotic protein Bax and caspase 3/8 expression and down regulation of anti-apoptotic proteins Bcl-2, Bcl-xl and Mcl-1 expression

Published:2021-01-08 Issue:1 Volume:29 Page:41-46
ISSN:1344-6835
Container-title:Annals of Cancer Research and Therapy
language:en
Short-container-title:Ann. Cancer Res. Therap.

Author:

Hamid Reza Ghaderi Jafarbeigloo ¹,Sedigheh Sheibani ²,Abbas Zakeri Bazmandeh ³

Affiliation:

1. Department of Basic Science, Payame Noor University

2. Department of Health Information Technology, School of Management and Medical Information Sciences, Shiraz University of Medical Sciences

3. Department of Medical Nanotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences

Publisher

The Japanese Society of Strategies for Cancer Research and Therapy

Subject

Pharmacology (medical),Cancer Research,Oncology

Link

https://www.jstage.jst.go.jp/article/acrt/29/1/29_41/_pdf

Reference29 articles.

1. 1) Arora, R. S. and Arora, B. (2016) Acute leukemia in children: A review of the current Indian data. South Asian journal of cancer. 5: 155–160.

2. 2) Arber, D. A., Orazi, A., Hasserjian, R., Thiele, J., Borowitz, M. J., Le Beau, M. M., Bloomfield, C. D., Cazzola, M. and Vardiman, J. W. (2016) The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood. 127: 2391–2405. doi: 10.1182/blood-2016-03-643544

3. 3) Burnett, A., Wetzler, M. and Lowenberg, B. (2011) Therapeutic advances in acute myeloid leukemia. J Clin Oncol. 29: 487–94. doi: 10.1200/JCO.2010.30.1820

4. 4) Goldman, S. L., Hassan, C., Khunte, M., Soldatenko, A., Jong, Y., Afshinnekoo, E. and Mason, C. E. (2019) Epigenetic modifications in acute myeloid leukemia: prognosis, treatment, and heterogeneity. Frontiers in genetics. 10: 133.

5. 5) Zebisch, A., Hatzl, S., Pichler, M., Wölfler, A. and Sill, H. (2016) Therapeutic resistance in acute myeloid leukemia: the role of non-coding RNAs. International journal of molecular sciences. 17: 2080.

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Effects and Mechanisms of Kaempferol in the Management of Cancers through Modulation of Inflammation and Signal Transduction Pathways;International Journal of Molecular Sciences;2023-05-11

2. A systematic review of anti-cancer roles and mechanisms of kaempferol as a natural compound;Cancer Cell International;2022-08-20

3. MSCs modifies the proliferation of leukemia MOLT-4 cells and induces their apoptosis through up-regulating Bax, caspase-3, and-8, and down-regulating Bcl-2 expression;Annals of Cancer Research and Therapy;2021-01-08

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