A case of cT4b recto-sigmoidal cancer obtained pathological complete response by preoperative chemotherapy with 4 cycles of mFOLFOX6 plus panitumumab

Author:

Kono Teppei12,Yokokawa Hideyuki12,Shidei Hiroaki12,Maeda Hiroyuki12,Miyano Yutaka1,Oyama Kunihiro1,Koike Taro1,Shiozawa Shunichi2,Oda Hideaki3,Yoshimatsu Kazuhiko12

Affiliation:

1. Department of Surgery, Saiseikai Kurihashi Hospital

2. Department of Surgery, Tokyo Women’s Medical University Medical Center East

3. Department of Pathology, Tokyo Women’s Medical University

Publisher

The Japanese Society of Strategies for Cancer Research and Therapy

Subject

Pharmacology (medical),Cancer Research,Oncology

Reference19 articles.

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2. 2) Van Cutsem, E., Köhne, C.H., Hitre, E., Zaluski, J., Chang Chien, C.R., Makhson, A., D’Haens, G., Pintér, T., Lim, R., Bodoky, G., Roh, J.K., Folprecht, G., Ruff, P., Stroh, C., Tejpar, S., Schlichting, M., Nippgen, J., Rougier, P. (2009) Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med. 360: 1408–1417. PMID: 19339720. doi: 10.1056/NEJMoa0805019

3. Panitumumab–FOLFOX4 Treatment and RAS Mutations in Colorectal Cancer

4. 4) Arnold, D., Lueza, B., Douillard, J.Y., Peeters, M., Lenz, H.J., Venook, A., Heinemann, V., Van Cutsem, E., Pignon, J.P., Tabernero, J., Cervantes, A., Ciardiello, F. (2017) Prognostic and predictive value of primary tumour side in patients with RAS wild-type metastatic colorectal cancer treated with chemotherapy and EGFR directed antibodies in six randomized trials. Ann Oncol. 28: 1713–1729. PMID: 28407110. doi: 10.1093/annonc/mdx175

5. 5) Yoshino, T., Arnold, D., Taniguchi, H., Pentheroudakis, G., Yamazaki, K., Xu, R.H., Kim, T.W., Ismail, F., Tan, I.B., Yeh, K.H., Grothey, A., Zhang, S., Ahn, J.B., Mastura, M.Y., Chong, D., Chen, L.T., Kopetz, S., Eguchi-Nakajima, T., Ebi, H., Ohtsu, A., Cervantes, A., Muro, K., Tabernero, J., Minami, H., Ciardiello, F., Douillard, J.Y. (2018) Pan-Asian adapted ESMO consensus guidelines for the management of patients with metastatic colorectal cancer: a JSMO-ESMO initiative endorsed by CSCO, KACO, MOS, SSO and TOS. Ann Oncol. 29: 44–70. PMID: 29155929. doi: 10.1093/annonc/mdx738

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