Platelet-Poor versus Platelet-Rich Plasma for the Treatment of Muscle Injuries

Author:

Raum George1,Kenyon Charles,Bowers Robert2

Affiliation:

1. Department of Physical Medicine and Rehabilitation, University of Pittsburgh Medical Center, Pittsburgh, PA

2. Department of Orthopedics, Department of Physical Medicine and Rehabilitation, Emory University, Atlanta, GA

Abstract

Abstract Muscle injury in sport results in significant lost time and potential for reinjury for athletes. Autologous blood product, namely, platelet-rich plasma (PRP), has been investigated for possible augmentation of the treatment timeline with prevention of reinjury; however, conflicting results have been identified. A growing body of basic science and clinical literature is forming that supports the use of platelet-poor plasma (PPP) for muscle injury. The purpose of this study was to provide a background of the basic science of PRP versus PPP for muscle injury and to identify and review the clinical evidence for both autologous blood products, including the author’s clinical experience utilizing the blood products. At the tissue level, PRP causes myoblast proliferation while PPP has led to myoblast induction, potentially identifying improved native muscle healing. Conflicting studies have been identified for the use of PRP for muscle injury. A growing body of positive results for PPP was identified, but high-quality comparative studies are needed.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Nonoperative Management of Medial Elbow Injuries in the Throwing Athlete;Current Physical Medicine and Rehabilitation Reports;2024-07-23

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