APPLICATION OF ANTIPSYCHOTICS OF LONG-TERM ACTION IN SCHIZOPHRENIA

Author:

Bibekova Zh. B.1ORCID,Strel’cov E. A.1ORCID,Makarchuk A. S.1ORCID

Affiliation:

1. Karaganda Medical University

Abstract

This literature review addresses the effectiveness and safety of long-acting antipsychotic therapy for schizophrenia. The results of randomized trials of recent years are described in detail. The efficacy of taking drugs at the following key research points was examined: the general clinical impression of the severity of the condition (CGI-S), the general clinical impression of the change in state during treatment (CGI-I), and the positive and negative syndrome scale (PANSS). A systematic literature search was conducted using the Scopus, Web of Science, MedLine, elibrary, and other databases.

Publisher

Rostov State Medical University

Subject

General Earth and Planetary Sciences,General Environmental Science

Reference45 articles.

1. Karam CS, Ballon JS, Bivens NM, Freyberg Z, Girgis RR, et al. Signaling pathways in schizophrenia: emerging targets and therapeutic strategies. Trends Pharmacol Sci. 2010;31(8):381– 90. doi: 10.1016/j.tips.2010.05.004

2. Xu Y, Ren J, Ye H. Association between variations in the disrupted in schizophrenia 1 gene and schizophrenia: A meta-analysis. Gene. 2018;651:94–99. doi: 10.1016/j. gene.2018.01.069.

3. National Institute of Mental Health Schizophrenia. Available online: https://www.nimh.nih.gov/health/topics/ schizophrenia/index.shtml. (accessed on 1 February 2016)

4. Zhong X, Shi H, Hou L, Chen B, Peng Q, et al. Neuropsychiatric features of Neurosyphilis: frequency, relationship with the severity of cognitive impairment and comparison with Alzheimer disease. Dement Geriatr Cogn Disord. 2017;43(5– 6):308–319. doi: 10.1159/000476060.

5. Owen MJ, Sawa A, Mortensen PB. Schizophrenia. Lancet. 2016;388(10039):86–97. doi: 10.1016/S0140-6736(15)01121- 6

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3