Affiliation:
1. Karaganda Medical University
Abstract
This literature review addresses the effectiveness and safety of long-acting antipsychotic therapy for schizophrenia. The results of randomized trials of recent years are described in detail. The efficacy of taking drugs at the following key research points was examined: the general clinical impression of the severity of the condition (CGI-S), the general clinical impression of the change in state during treatment (CGI-I), and the positive and negative syndrome scale (PANSS). A systematic literature search was conducted using the Scopus, Web of Science, MedLine, elibrary, and other databases.
Publisher
Rostov State Medical University
Subject
General Earth and Planetary Sciences,General Environmental Science
Reference45 articles.
1. Karam CS, Ballon JS, Bivens NM, Freyberg Z, Girgis RR, et al. Signaling pathways in schizophrenia: emerging targets and therapeutic strategies. Trends Pharmacol Sci. 2010;31(8):381– 90. doi: 10.1016/j.tips.2010.05.004
2. Xu Y, Ren J, Ye H. Association between variations in the disrupted in schizophrenia 1 gene and schizophrenia: A meta-analysis. Gene. 2018;651:94–99. doi: 10.1016/j. gene.2018.01.069.
3. National Institute of Mental Health Schizophrenia. Available online: https://www.nimh.nih.gov/health/topics/ schizophrenia/index.shtml. (accessed on 1 February 2016)
4. Zhong X, Shi H, Hou L, Chen B, Peng Q, et al. Neuropsychiatric features of Neurosyphilis: frequency, relationship with the severity of cognitive impairment and comparison with Alzheimer disease. Dement Geriatr Cogn Disord. 2017;43(5– 6):308–319. doi: 10.1159/000476060.
5. Owen MJ, Sawa A, Mortensen PB. Schizophrenia. Lancet. 2016;388(10039):86–97. doi: 10.1016/S0140-6736(15)01121- 6
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献