Affiliation:
1. Astrakhan State Medical University
Abstract
Objective: to study and compare the influence of such factors as: gender, age, family status, level of education and the frequency of determination of the international normalized ratio (INR) on the compliance of patients after mitral valve replacement (MC) with mechanical prostheses in dynamics - after 6 and 12 months. Materials and methods: it were analyzed data of 260 patients after MC prosthetics with mechanical bicuspid prostheses. The Morisky-Green test was used to assess compliance.Results: the most committed to treatment were female, middle-aged persons with secondary specialized and higher education, as well as married persons. Among patients who monitored INR on a monthly basis, the percentage of compliant patients was higher compared to patients where this indicator was determined less than once a month. The dynamics of a decrease in the number of compliant patients after 12 months of follow-up was established. Conclusions: the data obtained indicate the need to carry out more active work on the formation of compliance with «vulnerable» categories of patients: with men, with elderly and young patients, with persons with secondary education, unmarried. The revealed tendency to decrease compliance after 12 months, regardless of the studied factor, indicates the importance of maintaining compliance in the long-term postoperative period. Also, the data obtained indicate the presence of a relationship between the multiplicity of INR control and compliance.
Publisher
Rostov State Medical University
Subject
General Earth and Planetary Sciences,General Environmental Science
Reference18 articles.
1. Zhu Z, Li Y, Meng x, Han j, Li Y, et al. New warfarin anticoagulation management model after heart valve surgery: rationale and design of a prospective, multicentre, randomised trial to compare an internet-based warfarin anticoagulation management model with the traditional warfarin management model. BMJ Open. 2019;9(12):e032949. DOI: 10.1136/bmjopen-2019-032949.
2. Gorbunova E.V., Odarenko Yu. N., Mamchur S.E., Kudryavtseva N.G., Salahov R.R. Improving efficiency and safety of anticoagulation therapy in patients with prosthetic heart valves. Complex Issues of Cardiovascular Diseases. 2015;(4):26-33. (In Russ.) DOI: 10.17802/2306-1278-2015-4-26-33
3. Mueller jA, Patel T, Halawa A, Dumitrascu A, Dawson NL. warfarin dosing and body mass index. Ann Pharmacother. 2014;48(5):584-8. DOI: 10.1177/1060028013517541.
4. wang x, xu B, Liang H, jiang S, Tan H, et al. Distribution characteristics and factors influencing oral warfarin adherence in patients after heart valve replacement. Patient Prefer Adherence. 2018;12:1641-1648. DOI: 10.2147/PPA.S172223.
5. Kudryavtseva NG, Nikolenko NV, Sakharova OI, Vasilchenko VL, Tumanova SA, et al. Long-term efficiency of training program for patients with artificial heart valves to improve theadherence to treatment and quality of life. Kardiologiya i Serdechno-Sosudistaya Khirurgiya. 2017;10(4):13-18. (In Russ.). DOI: 10.17116/kardio201710413-18