Affiliation:
1. Russian Medical Academy of Continuing Professional Education; Botkin City Clinical Hospital
2. Russian Medical Academy of Continuing Professional Education
3. Botkin City Clinical Hospital
Abstract
Kidney cancer (KCa) is one of the greatest challenges in oncological urology due to the increase in morbidity and mortality rates annually. In the treatment of KCa, preservation of renal function is an important objective, in addition to achieving oncological results. The article presents the experience of treatment of 175 KCa-patients of pT1a – T2aN0M0 stages, who underwent nephron-saving surgery (NSS) with preventive hemostatic sutures. Functional outcomes of NSS were studied in the groups without cross-linking (group 1; n = 150) and with cross-linking of the renal pedicle (group 2; n = 25). Kidney resection with prophylactic suturing has been shown to allow removal of a tumour of almost any localisation. By avoiding cross-linking of the renal pedicle during surgery, post-ischemic changes in the renal parenchyma are minimised. Thus, one month after surgery, the perfusion indexes in groups 1 & 2 were 45.2 ± 3.0% vs 35.5 ± 3.3%; renal indexes were 44.8 ± 2.4% vs 39.1 ± 1.4%; areas of the functioning parenchyma were 52.0 ± 10.0% vs 35.0 ± 9.0%, respectively.
Publisher
Rostov State Medical University
Reference16 articles.
1. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin. 2011;61(2):69-90. Erratum in: CA Cancer J Clin. 2011;61(2):134. DOI: 10.3322/caac.20107
2. Aliaev Y., Akhvlediani N., Fiev D., Petrovskiy N. Possibilities of visualization methods in diagnostics and monitoring of kidney tumors. Experimental & clinical urology. 2011;(2–3):96-97. (In Russian). eLIBRARY ID: 17328514; EDN: OPFEZB
3. Gill IS, Kavoussi LR, Lane BR, Blute ML, Babineau D, Colombo JR Jr, Frank I, Permpongkosol S, Weight CJ, Kaouk JH, Kattan MW, Novick AC. Comparison of 1,800 laparoscopic and open partial nephrectomies for single renal tumors. J Urol. 2007;178(1):41-6. DOI: 10.1016/j.juro.2007.03.038
4. Ivanov A.P., Chernyshev I.V., Tyuzikov I.A. Optimization of spiral computed tomography protocol in the diagnosis of renal tumors. Cancer Urology. 2011;7(2):18-21. (In Russian). DOI: 10.17650/1726-9776-2011-7-2-18-21
5. Van Poppel H, Da Pozzo L, Albrecht W, Matveev V, Bono A, Borkowski A, Colombel M, Klotz L, Skinner E, Keane T, Marreaud S, Collette S, Sylvester R. A prospective, randomised EORTC intergroup phase 3 study comparing the oncologic outcome of elective nephron-sparing surgery and radical nephrectomy for low-stage renal cell carcinoma. Eur Urol. 2011;59(4):543-52. DOI: 10.1016/j.eururo.2010.12.013