New treatment options for bladder cancer patients: based on ASCO 2022 materials and beyond

Author:

Zyatchin I. V.1ORCID,Reva S. A.2ORCID

Affiliation:

1. Pavlov First Saint-Petersburg State Medical University (Pavlov University)

2. Pavlov First Saint-Petersburg State Medical University (Pavlov University); Petrov National Medical Research Center of Oncology

Abstract

Bladder cancer is the fourth most common cancer worldwide and the eighth leading cause of cancer mortality in men. The advent of new systemic therapies, including PD-1 and PD-L1 inhibitors, and advances in biomarker development have revolutionized the treatment of this disease. The current guidelines of the National Comprehensive Cancer Network (NCCN) support the inclusion of some new therapies in clinical practice. Over the past decade, many approvals for immuno-therapeutic agents have been obtained. Since bladder cancer is characterized by a high frequency of mutations, there has been a widespread introduction of medicines from the group of immune checkpoint inhibitors. All studies from this review were presented at a recent meeting of the American Society of Clinical Oncology (ASCO) and published in reputable journals.

Publisher

Rostov State Medical University

Reference9 articles.

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