Importance of Visceral Obesity and Testosterone Deficiency in the formation of metabolic disorders in men

Abstract

Background. During a long time, men appraise the problem of overweight as a natural process of aging in the conditions of social demand and physical inactivity. Therefore, there is usually no reason to see a doctor and conduct a clinical examination. In this regard, obesity-associated metabolic diseases are often diagnosed late in the complication stage.Objective. Assessing the effects of obesity and androgen deficiency on the development of metabolic disorders in men.Materials and methods. 120 men with obesity aged 29–56 years who considered themselves healthy were examined. The patients were divided into two groups: in-group 1 included 56 people with a normal level of total testosterone (T), in-group 2 included 64 people with a level of total T less than 12.1 mmol / l, accordingly. The main indicators of carbohydrate, lipid, purine metabolism, and the level of sex hormones were investigated.Results. Аnalysis of the metabolic status of obese men who considered themselves completely healthy revealed a high incidence of dyslipidemia, arterial hypertension, insulin resistance (IP), carbohydrate metabolism disorders and purine metabolism, and fatty hepatosis. The most significant changes were identified in the group of patients with testosterone deficiency.Conclusion. Visceral obesity in men is a high-risk factor for the formation of metabolic disorders. Androgen deficiency completed obesity leads to the formation of more severe metabolic changes in patients and the development of erectile dysfunction. Men with visceral obesity, even in the absence of actively complain need careful examination. It should include, along with the assessment of biochemical indicators of metabolic status, also control of the level of total serum testosterone.